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Test · Diagnostics

IHC Kappa And Lambda Light Chain

Free home sample collection, physician reviewedSubmit Tissue in 10% formal-saline OR formalin fixed paraffin embedded Tissue Block. Ship at room temperatureReports inBloodSample

Kappa or lambda immunoglobulin light chains pair with immunoglobulin heavy chains to form complete immunoglobulin molecules. These proteins serve as receptors for antigens in B lymphocytes and are secretory products of plasma cells, forming the humoral arm of the immune system. Because individual B cells or plasma cells synthesize immunoglobulin containing either kappa or lambda light chains, but not both, immunoperoxidase stains for light chains can be applied to lymphocyte and plasma cell populations as a marker of clonality and B-cell lineage.

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