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Test · Diagnostics

FISH: Synovial Sarcoma

Free home sample collection, physician reviewed2 Working Days Cut Off 10:00 AMReports inBloodSample

Synovial Sarcoma accounts for 5-10% of soft-tissue sarcomas and majority (90%) of them carry the t(X;18) translocation. This translocation results in the fusion of the SYT gene at 18q11 with either SSX1/SSX2 gene or rarely with SSX4 gene. Detection of this translocation is highly specific for Synovial Sarcoma and it is seen in all the three histological variants namely monophasic, biphasic & poorly differentiated.

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