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Test · Diagnostics

Treponema Pallidum (Syphilis) Qualitative Realtime PCR

Free home sample collection, physician reviewed3 daysReports inBloodSample

Syphilis (Treponema pallidum DNA), Qualitative Real-Time PCR - The Syphilis (Treponema pallidum) DNA, Qualitative Real-Time PCR is a molecular assay used for the direct detection of T. pallidum nucleic acid (DNA) in patient specimens to aid in the diagnosis of syphilis. Moist lesion (exudate) specimens collected during primary (and possibly secondary) syphilis can be tested in seronegative patients. Neonatal cerebral spinal fluid (CSF) can also be considered for testing as part of the laboratory evaluation in suspected cases of congenital syphilis. There is insufficient data to guide recommendations in suspected cases of adult neurosyphilis. Molecular testing in lesion specimens from adult patients is generally used in cases where serologic results do not correlate with clinical signs and symptoms suggestive of syphilis, including seronegative patients. In neonates being evaluated for congenital syphilis, PCR testing of suspicious lesions or CSF can be considered as supplemental to other laboratory testing including nontreponemal serologic tests (eg, RPR or VDRL). This assay may provide a rapid diagnosis during primary syphilis if organism is detected. A negative PCR result does not rule out infection. PCR testing during secondary syphilis has limited value compared to serologic testing. This assay does not detect antibodies against T. pallidum and therefore should not be used in place of treponemal and nontreponemal serologic tests. Antibody testing using the traditional or reverse algorithm is still considered the primary method for screening and diagnosis of syphilis.

₹3,500—Members pay ₹3150