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Test · Diagnostics

MSI (MMR) By IHC

Free home sample collection, physician reviewedDaily , Report 7 DaysReports inBloodSample

Microsatellite markers can be used to detect a form of genetic instability called Microsatellite Instability (MSI). MSI is a consequence of germline or somatic inactivation of mismatch repair genes including MSH2, MSH6, MLH1 & PMS2. This panel studies mismatch repair proteins in Hereditary Nonpolyposis Colorectal cancer (HNPCC) or Lynch syndrome. About 15% of patients having MSI tumors have Lynch syndrome while remaining have a sporadic form of Colorectal carcinoma (CRC). 95% of patients with Lynch syndrome have MSI.

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