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Test · Diagnostics

IHC TTF1

Free home sample collection, physician reviewedSubmit Tissue in 10% neutral buffered formaline or fixed paraffin embedded Block. Ship at room temperature. Provide histopathology report & other clinical history.Reports inBloodSample

Thyroid transcription factor 1 (TTF1) is a nuclear protein (detected by the chromogen 3,3'-diaminobenzidine) expressed in thyroid follicular cells, type II pneumocytes, and a subset of bronchial cells. Keratin 5 is a type II cytokeratin (detected by the chromogen fast red) that dimerizes with the type I cytokeratin 14 forming intermediate filaments in the basal layer of the epidermis. Keratin 5 is useful for differentiating squamous cell carcinoma (KRT5 positive) from pulmonary adenocarcinomas (KRT5 negative). This immunostain is often included in a panel to identify the primary site for carcinomas of unknown origin.

₹2,100—Members pay ₹1890