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Test · Diagnostics

IHC Ki67

Free home sample collection, physician reviewedSubmit Tissue in 10% formal-saline OR formalin fixed paraffin embedded Tissue Block. Ship at room temperatureReports inBloodSample

Ki-67 is a nuclear protein playing a pivotal role in maintaining cell proliferation. Ki-67 is present in all non-G0 phases of the cell cycle. Beginning in the mid-G1, the level increases through S and G2 to reach a peak in M phase. In the end of M phase, it is rapidly catabolized. Ki-67 has been employed as a marker of proliferation and hence, prognosis in neoplasms of many types such as Malignant lymphomas, prostatic and breast Adenocarcinomas, Astrocytic neoplasms and Soft tissue neoplasms. Ki-67 is an established prognostic biomarker in breast cancer. It is widely used as a marker of proliferation.

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