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Test · Diagnostics

IHC ALK

Free home sample collection, physician reviewedDaily , Report 5 DaysReports inBloodSample

A subset of anaplastic large-cell lymphomas shows overexpression of anaplastic lymphoma kinase (ALK-1) protein, resulting from a translocation involving the ALK1 gene. The abnormal ALK-1 expression can be in a nuclear or cytoplasmic distribution. Overexpression of ALK-1 protein is also useful in the diagnosis of lung adenocarcinoma and inflammatory myofibroblastic tumor. In normal tissue ALK-1 is negative.

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